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Nutrients to Reduce Homocysteine

What is Homocysteine?

Homocysteine is quite simply the major cause of heart problems in the world!

During one piece of clinical research that was carried out, every single heart patient whose homocysteine was measured was found to have raised levels. The statistical correlation between raised cholesterol levels and cardiovascular problems is far weaker.

Homocysteine has been shown to cause damage to the artery walls, forming sites for plaque build-up and resulting in angina, heart attack and strokes. This molecule is an altered amino acid formed during normal metabolism. It is produced  from methionine and is then converted into either cystathione or back into methionine. Homocysteine can damage artery walls, but neither methionine nor cystathione do this.

The body with adequate supplies of the necessary nutrients will efficiently convert homocysteine to cystathione or back to methionine. The conversion of homocysteine to cystathione requires vitamin B6, and the conversion of homocysteine back to methionine requires the donation of methyl (CH3) groups. Nutrients containing methyl groups are known as methyl donors.

Which Nutrients Will Help?

Trimethylglycine (TMG)

This is a very efficient methyl donor. It is actually an extract from sugar beet. Being a methyl donor, it aids the conversion of homocysteine back to methionine. In addition to this, it lowers cholesterol levels and total blood lipids (fats). An extremely effective protector for the cardiovascular system.

Vitamin B12

This also acts as a methyl donor, to help convert homocysteine back to methionine.

Folic Acid

As far as homocysteine levels are concerned, this vitamin acts in the same way as vitamin B12.

Vitamin B6

As mentioned above, this vitamin is needed for the conversion of homocysteine to cystathione, and those with low levels of vitamin B6 may be five times more likely to have a heart attack than those with good levels. It should be noted that some people may not convert vitamin B6 into its active form, pyridoxal 5-phosphate (P5P). Supplemen­tation of this co-enzyme may therefore sometimes be necessary.


Much publicity has been given, over many years, to the dangers of high cholesterol in causing cardiovascular problems, and a massive industry has grown in both drug and food production because of this. Could it be that when it is found in plaque, cholesterol is merely doing its job of repairing damage?

We feel that the damage to artery walls is the major cause of plaque build-up. The causes of arterial damage are high blood pressure, free radical damage and high homocysteine levels. The reduction of high blood pressure is a subject in itself, but avoiding high homocysteine levels will avoid one of the major factors, and the method is simple:

Try to find a supplement containing all of the above-mentioned nutrients in adequate quantities.

These nutrients will have further beneficial effects in addition to their help for the cardiovascular system. For instance, vitamin B6, folic acid and vitamin B12 also have beneficial effects on the nervous system.

To buy any of these products, click this link: www.NationalNutrition.co.uk